Thursday, June 30, 2011

tumefactive multiple sclerosis

tumefactive multiple sclerosisTumefactive multiple sclerosis is a condition in which the central nervous system of a person has multiple demyelinating lesions with typical characteristics for those of standard multiple sclerosis, including a size greater than 2 cm, presence of a mass effect, edema, or ring enhancement.

These atypical characteristics can mimic other diseases, lead to misdiagnosis, and may require brain biopsy for diagnosis. One Mayo Clinic study found that 6% of all lesions with T2 hypointense borders on MRI were in fact tumefactive multiple sclerosis lesions. The more common pathologies included gliomas (40%), metastases (30%) and abscesses (8%).

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